Cannabis, Anxiety, and Depression What You Need to Know

by | Mar 17, 2025

Anxiety and depression are challenging topics, and managing these conditions daily can feel overwhelming. Like many of you, I’ve had my fair share of days where managing mental health feels like climbing a never-ending mountain. Fortunately, knowledge is power, and together, we can address the complicated but promising relationship between cannabis, anxiety, and depression.

Two of the Main Players: THC & CBD

When exploring cannabis for mental health, two primary compounds often take center stage: THC and CBD. THC, or tetrahydrocannabinol, is the psychoactive compound responsible for the “high” sensation cannabis is known for. In small doses, THC can help alleviate anxiety, temporarily lift your mood, and provide a sense of relaxation. However, caution is necessary since higher doses of THC can have the opposite effect, potentially increasing anxiety, paranoia, or uneasiness. CBD, or cannabidiol, on the other hand, does not cause psychoactive effects. It is widely recognized for its calming properties, helping users manage anxiety and depressive symptoms without the sensation of feeling “high.”

Terpenes & Cannabis Strains: What to Look For: 

If you find that you are sensitive to how cannabis affects you, you might want to learn a bit more about terpenes. They are the essential oil of the plant (they are found in all plants and some insects) and there are normally many varieties found in every cannabis plant. Licensed Producers are who grow and manufacture cannabis and they will usually list out the top 3 terpenes on the packaging and sometimes the terpene totals. This is another factor to keep in mind when choosing your strains aside from lineage and THC total. Why is this, you might be wondering? Well, when a Licensed Producer  gets their overall terpenes at 1%, that is pretty standard, but when we are looking at plants that are producing 1%-5%  then terpenes also take a role in cannabis. 

Limonene is a terpene that has been found to increase anxiety, especially when found in a strong Sativa plant like Ultra Sour, Green Crack or Green Crush. 

So my suggestion is to look for Indica or a Hybrid plant as they are generally more calming and relaxing. Myrcene or Humulene are great terpenes to look for if you are looking to wind down. These two terpenes are predominantly found more in Indica plants. Some strains to look for are OG Kush and Grape Ape. 

Did you know that back in the day Chinese Doctors used to prescribe patients who were dealing with Stress and Depression to go for walks in the woods? They did this because when you walk in nature you are naturally decompressing but as well you are taking in all the terpenes in the air, with Pinene being the leading terpene found in most cannabis plants and pine trees. It is another great terpene relaxing to look for when choosing the best strain for yourself. 

Cannabis & Anxiety: Friend or Foe?

Cannabis and anxiety have a complicated relationship, and understanding how to approach cannabis use safely is critical. Products rich in CBD typically help reduce anxiety, improve sleep quality, and enhance relaxation. These CBD-rich products have become increasingly popular among individuals looking for relief without psychoactive effects. THC, however, can be a bit trickier to navigate. In small amounts, THC can soothe anxiety symptoms and provide short-term relief. Yet, higher doses could lead to heightened anxiety or panic attacks. For those new to cannabis or sensitive to THC, it’s best to start with very low doses and increase gradually to find a comfortable level of relief. As well, keep a cannabis journal and record how you felt, what you like about the experience and if you want to try that again. Cannabis in all forms is a very personal journey and everyone reacts differently to cannabis because of our Endocannabinoid Systems. 

Cannabis & Depression: A Delicate Balance

When it comes to depression, cannabis isn’t straightforward either. Many individuals initially turn to cannabis for temporary mood improvement, stress relief, or relaxation. While it can provide immediate comfort, long-term use of THC-rich cannabis may inadvertently worsen depressive symptoms. Regular heavy use can reduce motivation, increase feelings of isolation, and contribute to lethargy—a state often referred to as “amotivational syndrome.” Conversely, CBD shows significant promise in supporting mood stabilization and alleviating depressive symptoms without the negative side effects often associated with THC. As with anxiety, moderation and careful attention to the products you choose are essential.

Cannabis & Mental Health

Another crucial factor to consider when evaluating cannabis for mental health is the age at which cannabis use begins. Research indicates that individuals who start using cannabis during adolescence face a higher risk of developing anxiety and depressive disorders later in life. The developing brain is particularly susceptible to the impact of cannabis. Conversely, adults who initiate cannabis use later in life generally experience fewer negative effects. Understanding this aspect emphasizes the importance of timing and careful consideration before beginning cannabis use, especially for younger individuals.

Choosing how you consume cannabis also plays a significant role in its effectiveness for managing anxiety and depression. Smoking or vaping provides fast-acting relief, making it a suitable option for immediate anxiety or stressful situations. However, the effects tend to wear off quickly. Edibles or cannabis-infused drinks, on the other hand, offer slower onset but longer-lasting effects. This makes them ideal for sustained anxiety or mood management, though they require careful dosing since their potency can sometimes surprise new users. Topical applications, such as CBD-infused creams, bath salts and lotions, can offer excellent relaxation benefits but typically don’t provide direct mental health relief. Personally, I find CBD oils and tinctures most effective, offering consistent, predictable, and long-lasting anxiety relief.

When selecting products, focus on your specific mental health needs. For anxiety relief, seek out CBD-rich or balanced THC/CBD strains such as Sundae Driver, available at our store in  pre-roll form CBD:CBG Cherry Blossom or Cherry Lemonade in bud form, also available in our store. These varieties provide calming effects without excessive stimulation or anxiety. If your primary concern is depression, CBD-dominant products tend to offer safer, more consistent results. Don’t hesitate to seek guidance from local budtenders; they’re knowledgeable resources that can help tailor your cannabis experience to your individual needs.

It’s equally important to consult your healthcare provider when incorporating cannabis into your mental health regimen, particularly if you’re currently taking antidepressants or other medications. Cannabis can interact with these medications, and professional guidance will ensure your safety and optimize your treatment approach.

While cannabis has potential benefits for managing anxiety and depression, it’s far from a magic cure. The key to successful cannabis use for mental health lies in moderation, careful selection of products, and personalized education. Listen closely to your body, start slowly, and remain informed about the effects cannabis has on your mental well-being. Remember, mental health is a shared journey—we’re all navigating these challenges together. Let’s continue the conversation openly and honestly, supporting one another as we explore the best paths toward emotional wellness.